Effect of 7-methoxytacrine and L-carnitine on the activity of choline acetyltransferase.

نویسندگان

  • J Bajgar
  • F Skopec
  • J Herink
  • J Patocka
  • J Kvetina
چکیده

Changes of choline acetyltransferase (ChAT) activity in the hippocampus and the basal ganglia were studied in rats treated i.p. with L-carnitine (CRT) and 7-methoxytacrine (7-MEOTA) (i.m.) separately or 3-days treated with L-carnitine and then with one administration of 7-MEOTA. Both compounds increased ChAT activity when administered separately. 3-day treatment of CRT followed by administration of 7-MEOTA normalized ChAT activity.

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عنوان ژورنال:
  • General physiology and biophysics

دوره 18 Spec No  شماره 

صفحات  -

تاریخ انتشار 1999